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Endoxifen. Endoxifen, also known as 4-hydroxy-N-desmethyltamoxifen, is a nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group as well as a protein kinase C (PKC) inhibitor. It is under development for the treatment of estrogen receptor -positive breast cancer and for the treatment of mania in bipolar disorder.
The Blind Side is a 2009 American sports drama film written and directed by John Lee Hancock. Based on the 2006 book of the same name by Michael Lewis , [2] the film tells the story of Michael Oher , a football offensive lineman who overcame an impoverished upbringing to play in the National Football League (NFL) with the help of Leigh Anne and ...
Zopiclone, sold under the brand name Imovane among others, is a nonbenzodiazepine used to treat difficulty sleeping. Zopiclone is molecularly distinct from benzodiazepine drugs and is classed as a cyclopyrrolone. However, zopiclone increases the normal transmission of the neurotransmitter gamma-aminobutyric acid (GABA) in the central nervous ...
zztop .com. ZZ Top [a] is an American rock band formed in Houston, Texas, in 1969. For 51 years, it consisted of vocalist-guitarist Billy Gibbons, drummer Frank Beard and bassist-vocalist Dusty Hill, until Hill's death in 2021. ZZ Top developed a signature sound based on Gibbons' blues style and Hill and Beard's rhythm section.
– Richard Wright The album was originally released in a gatefold LP sleeve designed by Hipgnosis and George Hardie. Hipgnosis had designed several of the band's previous albums, with controversial results; EMI had reacted with confusion when faced with the cover designs for Atom Heart Mother and Obscured by Clouds, as they had expected to see traditional designs which included lettering and ...
West Side Story is a 2021 American musical romantic drama film directed and co-produced by Steven Spielberg from a screenplay by Tony Kushner. The second feature-length adaptation of the 1957 stage musical of the same name, [9] [10] it stars Ansel Elgort and Rachel Zegler in her film debut with Ariana DeBose, David Alvarez, Mike Faist, and Rita ...
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