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Tadalafil is an annulated 2,5-diketopiperazine. [25] It is also a 1,2,3,4-tetrahydro-β-carboline. Tadalafil can be synthesized starting from (D)-tryptophan methyl ester and piperonal via a Pictet–Spengler reaction. This is followed by condensations with chloroacetyl chloride and methylamine to complete the diketopiperazine ring: [26]
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The American Rescue Plan Act of 2021, also called the COVID-19 Stimulus Package or American Rescue Plan, is a US$1.9 trillion economic stimulus bill passed by the 117th United States Congress and signed into law by President Joe Biden on March 11, 2021, to speed up the country's recovery from the economic and health effects of the COVID-19 pandemic and recession. [1]
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Stree 2 grossed ₹9.40 crore from paid previews in select theatres the day before its release, breaking the previous record held by Chennai Express. Released alongside Vedaa and Khel Khel Mein on Independence day, the film went on to gross ₹64.80 crore, marking the second-highest opening day for a Hindi film, behind only Jawan (2023).
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