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Clark International Airport ( IATA: CRK, ICAO: RPLC ), known as Diosdado Macapagal International Airport from 2003 to 2014, is an international airport covering portions of the cities of Angeles and Mabalacat within the Clark Freeport Zone in the province of Pampanga, Philippines. It is located 80 kilometers (50 mi) [6] northwest of Manila.
Adapter molecule crk is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. This protein has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction.
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