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While definitive sites of metabolism have not been firmly established, there are several metabolites worthy of note. N-Desethylbrinzolamide is an active metabolite of the parent compound, and thus exhibits carbonic anhydrase inhibitory activity (largely carbonic anhydrase-I, when in the presence of Brinzolamide) and also accumulates in the erythrocytes.
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Fundus photographs of the right eye (left image) and left eye (right image), as seen from the front (as if face to face with the viewer). Each fundus has no sign of disease or pathology. The gaze is into the camera, so in each picture the macula is in the center of the image, and the optic disc is located towards the nose. Both optic discs have ...
Aces around, dix or double pinochles. Score points by trick-taking and also by forming combinations of cards into melds.
Before 1968, vision research at NIH was funded and overseen by the National Institute of Neurological Disease and Blindness [2] (now known as the National Institute of Neurological Disorders and Stroke), which was established in 1950, after President Harry S. Truman signed the Omnibus Medical Research Act. [2]
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